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Growth Factors - IGF1
A General Introduction (Insulin-like Growth Factor-1) (IGF1)
is released by many different tissues throughout the body and affects almost
every cell to some degree. Major organs that synthesize IGF1 are the human
placenta, heart, lung, kidney, liver, pancreas, spleen, small intestines,
testes, ovaries, large intestines, brain, bone and pituitary. Humans produce
approximately 10 milligrams of IGF1 per day until about 30 years old whereby
production decreases with aging. IGF1 has similarities to insulin and possesses
potent anabolic and cell growth effects. IGF1 is also important for its affect
on development, diabetes and other chronic diseases. IGF1 is primarily secreted
by the liver in response to a signal from human growth hormone (hGH).
The major target tissues affected by the IGF1 in combination with the
hGH signal are muscle, cartilage, bone, liver, kidney, nerves, skin and lungs.
IGF1 is known as a 'progression' factor. IGF1 assists competent cells toward
cell division and often that is all cells need for successful activation. IGF1
cooperates with PDGF to increase the cell's ability to complete DNA synthesis.
IGF1 not only helps cell growth by division, but also by enhancing cell
specialization. Hormonal functions such as the anabolic (constructive) activity
of hGH depends on the production and presence of IGF1 to achieve positive
results.
- IGF1 increases physical performance, mental performance, and physical
endurance in healthy individuals.
- IGF1 communicates an anabolic signal to cells, regulating cell
division and differentiation as the muscle acquires an increased need for
strength or as injury to the muscle is incurred.
- IGF1 promotes the growth of muscle and bone.
- IGF1 acts within the nervous system and is critical for the growth
and development of nerve cells.
- IGF1 maintains a high level of cell communication at the
neuromuscular junction, where the cooperation between the nerve and muscle
cells take place.
Studies show that after a one week period of strenuous exercise, blood
levels of IGF1 are significantly increased due to either regenerative processes
from muscle injury or higher requirements in muscles to handle the weight load.
In aging cells, there is a greater need for more IGF1 in order to move cells
out of the 'resting phase' and into a growth phase of the cell cycle. A slower
growth of cells during the aging process correlates with a higher requirement
of IGF1 than the body supplies. The increase in cellular communication from an
addition of IGF1 may bring the aging, slower cells back into the balanced state
optimizing cell activity and tissue/organ performance.
Homeopathic IGF1 Homeopathic IGF1 works in many different
areas of the body to facilitate and improve cellular performance. A recent
independent double-blind, placebo-controlled clinical testing of homeopathic
IGF1 demonstrated effectiveness in the nervous, reproductive, musculo/skeletal,
and gastrointestinal systems. Specifically, homeopathic IGF1 improved energy
levels and physical performance, respiratory conditions, and relieved symptoms
of PMS and menopause. It also relieved muscle and bone aches and pains, joint
stiffness, inflammation in the body, improved mental concentration and clarity
and positively affected appetite. Increases in lean body mass also have been
anecdotally reported.
Homeopathic IGF1 balances weight by helping the body to achieve its
ideal weight, whether that means losing weight for people too heavy, or gaining
weight for people too lean. IGF1 is believed to bring aging, resting cells back
into a balanced state optimizing cell activity and tissue performance.
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